APLEpy: A Python modeling tool for linear and mixed-integer linear programs.
Pyomo: Pyomo is a collection of Python optimization-related packages that supports a diverse set of optimization capabilities for formulating and analyzing optimization models.
CVExp: Expression Tree Builder and Translator based on a Controlled Vocabulary
CVXOPT (license: GPL3), a tool for convex optimization which defines its own matrix-like object and interfaces to FFTW, BLAS, and LAPACK.
cvxpy A Python package for modeling convex optimization problems
DEAP: Distributed Evolutionary Algorithms in Python]